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Page 1
A non-canonical scaffold-type E3 ligase complex mediates protein UFMylation.
Peter JJ, Magnussen HM, DaRosa PA, Millrine D, Matthews SP, Lamoliatte F, Sundaramoorthy R, Kopito RR, Kulathu Y. Peter JJ, et al. Among authors: magnussen hm. EMBO J. 2022 Nov 2;41(21):e111015. doi: 10.15252/embj.2022111015. Epub 2022 Sep 19. EMBO J. 2022. PMID: 36121123 Free PMC article.
The UFM1 E3 ligase recognizes and releases 60S ribosomes from ER translocons.
Makhlouf L, Peter JJ, Magnussen HM, Thakur R, Millrine D, Minshull TC, Harrison G, Varghese J, Lamoliatte F, Foglizzo M, Macartney T, Calabrese AN, Zeqiraj E, Kulathu Y. Makhlouf L, et al. Among authors: magnussen hm. Nature. 2024 Mar;627(8003):437-444. doi: 10.1038/s41586-024-07093-w. Epub 2024 Feb 21. Nature. 2024. PMID: 38383789 Free PMC article.
Human UFSP1 is an active protease that regulates UFM1 maturation and UFMylation.
Millrine D, Cummings T, Matthews SP, Peter JJ, Magnussen HM, Lange SM, Macartney T, Lamoliatte F, Knebel A, Kulathu Y. Millrine D, et al. Among authors: magnussen hm. Cell Rep. 2022 Aug 2;40(5):111168. doi: 10.1016/j.celrep.2022.111168. Cell Rep. 2022. PMID: 35926457 Free PMC article.
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Magnussen HM, Ahmed SF, Sibbet GJ, Hristova VA, Nomura K, Hock AK, Archibald LJ, Jamieson AG, Fushman D, Vousden KH, Weissman AM, Huang DT. Magnussen HM, et al. Nat Commun. 2020 Apr 29;11(1):2094. doi: 10.1038/s41467-020-15783-y. Nat Commun. 2020. PMID: 32350255 Free PMC article.
Differential requirements for MDM2 E3 activity during embryogenesis and in adult mice.
Humpton TJ, Nomura K, Weber J, Magnussen HM, Hock AK, Nixon C, Dhayade S, Stevenson D, Huang DT, Strathdee D, Blyth K, Vousden KH. Humpton TJ, et al. Among authors: magnussen hm. Genes Dev. 2021 Jan 1;35(1-2):117-132. doi: 10.1101/gad.341875.120. Epub 2020 Dec 17. Genes Dev. 2021. PMID: 33334825 Free PMC article.
11 results